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AKB: Biologische Physik

AKB 50: Poster Session "Biological Physics"

AKB 50.59: Poster

Friday, March 12, 2004, 10:30–13:00, B

Microfabricated label-free biosensors — •Jürgen Fritz — School of Engineering and Science, International University Bremen

Label-free microfabricated biosensors offer the advantage of real-time and highly parallel detection of biomolecules. Two recent examples of label-free silicon biosensors are presented: nanomechanical cantilever sensors which detect biomolecules by surface stress and electronic field-effect sensors, which detect biomolecules by their intrinsic charge. We will discuss applications, advantages, and limits of both sensors for real-time detection of nucleic acids and proteins.

J. Fritz et al., Translating biomolecular recognition into nanomechanics, Science 288 (2000) 316.

J. Fritz et al., Electronic detection of DNA by its intrinsic molecular charge, PNAS 99 (2002) 14142.