Regensburg 2007 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 1: Medizinische Bildgebung I
ST 1.8: Vortrag
Montag, 26. März 2007, 12:15–12:30, Ch 12.0.16
Detailed Studies of Proton NMR Relaxation Times in the Presence of Magnetic Nanoparticles — •Christian Höhl1, Nouri Elmiladi1, André Engelbertz1, Maurice Schlichtenmayer1, Fritz Vögtle2, and Karl Maier1 — 1Helmholtz - Institut für Strahlen- und Kernphysik Bonn — 2Kekulé-Institut für Organische Chemie und Biochemie Bonn
In magnetic resonance imaging (MRI) small magnetic particles of iron oxide (SPIO) are used as an additional contrast agent. The contrast is obtained by a decrease of the relaxation times T1 and T2, varying with the concentration of the SPIO. We did detailed measurements on the influence on T1 and T2 in the presence of SPIO at various concentrations and particle sizes. We observed huge differences of Δ T1 / Δ T2 at particles sizes between 20nm and 1000nm. The influence of resonant ultrasound pulses on T1 and T2 in presence of SPIO is discussed.