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BP: Fachverband Biologische Physik

BP 9: Actin Dynamics

BP 9.5: Talk

Tuesday, March 24, 2009, 11:45–12:00, ZEU 260

Polymerization forces of interacting filaments — •Jaroslaw Krawczyk and Jan Kierfeld — TU Dortmund, Fakultät Physik, 44221 Dortmund

Many cellular processes are driven by polymerization of filamentous proteins. Using stochastic simulations based on the Gillespie algorithm we investigate force-generation by polymerizing groups of filaments or protofilaments and study the influence of an attractive interaction between filaments on the polymerization dynamics. We find that the force-velocity characteristics, the stall force and maximal growth velocity of the filament assembly depend sensitively on the presence of interactions.