Hannover 2010 – wissenschaftliches Programm
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SYMP: Symposium Plasma in Biology and Medicine
SYMP 1: Plasma in Biology and Medicine (SYMP)
SYMP 1.1: Hauptvortrag
Mittwoch, 10. März 2010, 14:00–14:30, A 001
Cold atmospheric argon plasma significantly decreases bacterial load of chronic wounds in patients — •Georg Isbary1, Wilhelm Stolz1, Hans-Ulrich Schmidt2, Tetsuji Shimizu3, Bernd Steffes3, Julia Zimmermann3, Tetyana Nosenko3, Wolfram Bunk3, Roberto Monetti3, and Gregor Morfill3 — 1Department of Dermatology, Allergology and Environmental Medicine, Hospital Munich-Schwabing, Germany — 2Department of Microbiology, Hospital Munich-Schwabing, Germany — 3Max Planck Institute for Extraterrestrial Physics, Garching, Germany
We are testing a new method of chronic wound treatment using a low-temperature argon plasma. The results of the clinical phase II of this study show a significant increase in the rate of germ reduction in plasma-treated wounds in comparison with wounds that received only standard wound care. This effect is found in all kinds of germs, regardless the resistance level. The observed bactericidal effect of plasma therapy relies on the synergy of UVR, charged particles, electric fields, ROS and RNS. The combination of these biologically active components makes plasma a promising tool for fighting multiresistant germs. The advantage of this indirect plasma device is that it can be designed and optimized for different purposes, such as germ specific biofilms or varying wound fluid compositions. Furthermore there is evidence that plasma can enhance wound healing itself.