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Dresden 2017 – scientific programme

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HL: Fachverband Halbleiterphysik

HL 86: New Materials

HL 86.10: Talk

Friday, March 24, 2017, 12:15–12:30, POT 112

Preparation and characterization of self-assembled monolayers on different semiconductive substrates for bio-sensing applications. — •Stefano Gremmo, Johannes Bartl, Martin Stutzmann, and Anna Cattani-Scholz — Walter Schottky Institut, Technische Universität München, München, Germany

Aim of the present work is to realize and characterize bio-interfaces based on self-assembled monolayers of phosphonic acids (SAMPs) stable under physiological conditions, to implement a label-free transduction mechanism for DNA detection. Such process is performed on different semiconductive substrates, such as ZnO and SiN, to investigate their characteristics and performance in detecting the target molecules.

SAMPs of (2-2-[2-hydroxy-ethoxy]-ethoxy-ethyl) phosphonic acid and 11-hydroxy-undecylphosphonic acid are generated on the substrates using a process based on tethering by aggregation and growth (T-BAG). By additional surface functionalization protocols, peptide nucleic acid (PNA) is covalently bound to biocompatible SAMPs interfaces.

Characterization of the electrochemical sensing ability of these new devices is achieved by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Structural and morphological properties are investigated by several surface sensitive techniques such as contact angle (CA) measurements, atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS).

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