Dresden 2017 – wissenschaftliches Programm
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HL: Fachverband Halbleiterphysik
HL 87: Carbon: Diamond and others
HL 87.1: Vortrag
Freitag, 24. März 2017, 09:30–09:45, POT 06
Towards optical dynamical nuclear spin polarization of metabolites — •Samuel Müller1, Jochen Scheuer1, Christoph Müller1, Ilai Schwarz2, Mathen Markham3, Pelayo Fernandez-Acebal2, Martin Plenio1, Boris Naydenov1, and Fedor Jelezko1 — 1Institut für Quantenoptik, Universität Ulm, Germany — 2Institut für Theoretische Physik, Universität Ulm, Germany — 3Element Six, Ltd., Ascot, UK
13C magnetic resonance spectroscopy allows a wide range of new applications in magnetic resonance imaging and in a first clinical study this technique already has been demonstrated for imaging prostate cancer [1]. However, due to its small gyromagnetic ratio and low abundance of 13C spins, hyperpolarization of the nuclear spins is required for increasing the sensitivity. In contrast to conventional methods for hyperpolarization at low temperatures and high magnetic field dynamical nuclear polarization (DNP) via optically pumped Nitrogen-Vacancy centers (NV) in diamond allows a high degree of polarization to be reached even at room temperature and low magnetic field. Here we demonstrate DNP of 1H nuclear spins in different molecules on the diamond surface using single shallow NV centers. This is an important step towards nuclear spin hyperpolarization of biomarkers such as 13C in metabolites, e.g. pyruvate.
[1] Nelson, Sarah J., et al. Science translational medicine (2013)