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Berlin 2018 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 54: Statistical Physics of Biological Systems I (joint session BP/DY)

DY 54.11: Vortrag

Donnerstag, 15. März 2018, 12:30–12:45, H 2013

Chemoattractant induced transient adaptation in the oscillatory cytoskeleton of motile amoeboid cells. — •Jose Negrete JR1,2, Alain Pumir3,4, Christian Westendorf4, Marco Tarantola4, Eberhard Bodenschatz4,5,6, and Carsten Beta71Max Planck Institute for the Physics of Complex Systems, Dresden, Germany — 2École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland — 3École Normale Supérieure de Lyon, Lyon, France — 4Max Planck Institute for Dynamics and Selforganization — 5University of Göttingen, Göttingen, Germany — 6Cornell University, Ithaca, USA — 7University of Potsdam, Potsdam, Germany

Dictyostelium discoideum presents oscillatory actin polymerization cycles which amplitude is mostly given by noise. We investigate the transient response on the actin polymerization activity in Dictyostelium discoideum induced by a short pulse of cAMP. The stimulation induces a transient response, of reduced amplitude and frequency, which time duration is stochastic and varies between cells. To model the observed actin behavior, we extend the description of noisy oscillator by introducing an inhibitory variable that acts as a timer for the transient phase.

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