Regensburg 2019 – wissenschaftliches Programm
PLV VII: Plenarvortrag
Mittwoch, 3. April 2019, 08:30–09:15, H1
Mechanics of Single Protein Molecules — •Matthias Rief — Physikdepartment der TU München, Garching, Germany
Proteins are amazing molecular machines that can fold into a complex three dimensional structure. Even though powerful structural methods have allowed us taking still photographs of protein structures in atomic detail, the knowledge about the pathways for conformational changes and the associated dynamics is still limited. Over the past 15 years, our group has developed single molecule mechanical methods to study the dynamics and mechanics of protein structures. In my talk I will illustrate how these methods can be used to investigate and control the conformational mechanics of individual proteins. Examples include protein folding as well as protein-protein interactions and enzyme mechanics.