Regensburg 2019 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 1: X-ray Imaging
ST 1.1: Vortrag
Montag, 1. April 2019, 15:00–15:15, H48
Dynamic X-ray Imaging at the Munich Compact Light Source — •Regine Gradl1, Martin Dierolf1, David Kutschke2, Lin Yang2, Otmar Schmid2, Franz Pfeiffer1, and Kaye S. Morgan1,3 — 1Chair of Biomedical Physics and Munich School of BioEngineering; Institute for Advanced Studies, Technical University of Munich, Garching, Germany — 2Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München, Neuherberg, Germany — 3School of Physics and Astronomy, Monash University, Clayton, Australia
In vivo dynamic respiratory phase-contrast x-ray imaging in small animal models is a powerful research tool, which can be used to increase physiological understanding, and accelerate new therapies towards the clinics. Previously, these experiments were mainly limited to synchrotron facilities. Here we present results for dynamic in vivo x-ray phase-contrast imaging obtained in a laboratory environment using the Munich Compact Light Source. By employing inverse Compton scattering instead of permanent magnet undulators, it is possible to shrink the storage ring to a few meters in circumference, generating brilliant, partially coherent and quasi-monochromatic x-rays. Two different experimental set-ups for dynamic phase-contrast imaging have been implemented at this source. Firstly, a grating interferometer which is used for imaging repeated motion (e.g. the breath cycle of a mouse) and secondly, a propagation-based imaging set-up for detecting irreversible changes. This presentation will describe the set-ups and current applications of these laboratory-based imaging systems.