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Regensburg 2019 – scientific programme

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ST: Fachverband Strahlen- und Medizinphysik

ST 4: Poster session

ST 4.6: Poster

Tuesday, April 2, 2019, 14:00–16:00, Poster B1

Investigation of the dependency of properties of a 4-layer DOI PET detector on the scintillator material — •Munetaka Nitta1, Giulio Lovatti1, Georgios Dedes1, Sodai Takyu2, Mohammad Safari1, Tim Binder1, Giovanni Vinci1, Taiga Yamaya2, Katia Parodi1, and Peter G. Thirolf11LMU, Munich, Germany — 2NIRS-QST, Chiba, Japan

We have started to design an in-beam PET system for the Small animal proton irradiator for research in molecular image-guided radiation-oncology (SIRMIO) project. The PET will image positron emitters generated by the proton beam or externally injected with radioactive tracers. To achieve both uniform high image resolution and high sensitivity, we require a PET detector with high spatial resolution and depth-of-interaction (DOI) identification capability. Here, the 4-layer DOI PET detector developed by the NIRS is a leading candidate. As a scintillator material, both LYSO and GAGG are candidates. LYSO is commonly used for PET detectors, but contains the radioactive isotope of Lu-176 which provides random coincidences for PET measurement as background. Such noise events might not be negligible due to the limited yield of generated positron emitters for pre-clinical treatment. Although the density of GAGG is lower than for LYSO, GAGG does not contain such radioactivity. In this study, we carried out simulations using Geant4 of both LYSO and GAGG-based 4-layer DOI PET detectors to investigate the dependency of the PET detector properties on the scintillator material. This work is funded by the European Research Council (ERC) under grant agreement number 725539.

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