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Regensburg 2019 – scientific programme

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ST: Fachverband Strahlen- und Medizinphysik

ST 6: Radiation Therapy

ST 6.3: Talk

Wednesday, April 3, 2019, 15:30–15:45, H48

Activation of Titanium Samples in Proton Therapy — •Claus Maximilian Bäcker1,2,3,4, Aaron Bley1, Christian Bäumer2,3,4, Pedro Fragoso Costa3,4,5, Marcel Gerhardt1, Ken Herrmann3,4,5, Samantha Kauer1,2,3,4, Kevin Kröninger1, Christian Nitsch1, Hilda Milani Siregar1, Beate Timmermann2,3,4,6, Jens Weingarten1, and Azad Yazgan1,2,3,41TU Dortmund, Lehrstuhl für Experimentelle Physik IV, 44227 Dortmund — 2Westdeutsches Protonentherapiezentrum Essen, 45122 Essen — 3Westdeutsches Tumorzentrum, 45122 Essen — 4Universitätsklinikum Essen, 45122 Essen — 5Universitätsklinikum Essen, Klinik für Nuklearmedizin, 45122 Essen — 6Universitätsklinikum Essen, Klinik für Partikeltherapie, 45122 Essen

Titanium is one of the most commonly used materials for implants. These implants might be activated in nuclear interactions of protons during proton therapy. Different radionuclides can be produced during the irradiation of those implants. For this study, simplified titanium samples are irradiated with clinical proton beams at different energies.

The activity of the produced radionuclides is measured using low-level gamma-ray spectrometry. With these results the nuclear activation cross sections can be calculated. Furthermore, activated titanium samples are scanned with preclinical PET/CT imaging. The PET/CT imaging method is used to estimate the β+ activity in the samples. The delayed response of secondary radiation from titanium might be used for in-vivo dose verification with off-line PET.

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