BPCPPDYSOE21 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 11: Poster A: Single Molecule, Multicellular, Bioimaging, Focus Sessions, etc.
BP 11.2: Poster
Montag, 22. März 2021, 16:30–19:00, BPp
Molecular Friction and Adhesion on Porous Membranes — •Kordula Schellnhuber1,2, Hanna Hübner2, Johanna Blass1, Markus Gallei2, and Roland Bennewitz1 — 1INM-Institut für Neue Materialien, Campus D.2.2 Universität des Saarlandes, 66123 Saarbrücken, Germany — 2Lehrstuhl für Polymerchemie, Naturwissenschaftlich-Technische Fakultät, Universität des Saarlandes, 66123 Saarbrücken, Germany
Understanding and controlling the dynamics of polymer-surface interactions are key to a functional design of nanoscale objects and to reveal mechanisms underlying biological processes. We study friction and adhesion of single polymers at the solid-liquid interface by means of atomic force microscopy (AFM) with focus on entanglement dynamics. As a model system, a single M13mp18 DNA-molecule with a length of 2.5 µm is attached to an AFM probe. Friction measurements are performed by moving the cantilever in parallel to the surface at a height of a few hundred nanometers. Deflection of the cantilever reveals adhesive interactions between the DNA polymer and the membrane. Entanglement of the DNA in the membrane pores is probed by adhesion measurements after varying waiting time at a constant height of few hundred nanometers above the surface.