BPCPPDYSOE21 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 4: Cell Mechanics II
BP 4.6: Vortrag
Montag, 22. März 2021, 12:40–13:00, BPa
Erythrocyte-erythrocyte aggregation dynamics under shear flow — •Mehdi Abbasi1, Alexander Farutin1, Hamid Ez-Zahraouy2, Abdelilah Benyoussef3, and Chaouqi Misbah1 — 1Univ Grenoble Alpes, CNRS, LIPhy, F-38000 Grenoble, France — 2LaMCScI, Faculty of Sciences, Mohammed V University of Rabat, Rabat 1014, Morocco — 3Hassan II Academy of Science and Technology, Rabat 10220, Morocco
In a previous work [Blood cells, molecules, and diseases 25, 339 (1999)], it has been shown that the Red blood cells (RBCs) aggregation process starts by the formation of RBC doublets. In this work we study, by means of numerical simulations, the dynamics of RBCs doublets under shear flow and the impact on rheology. We present a rich phase diagram of RBCs doublets configurations showing features never evoked before. In particular, we show that RBCs doublet may be robust even for very high shear stress compromizing oxygen delivery to organs and tissues. A link to pathological conditions (several common blood diseases) is highlighted.