SKM 2023 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 12: Biopolymers and Biomaterials (joint session BP/CPP)

BP 12.2: Vortrag

Mittwoch, 29. März 2023, 09:45–10:00, TOE 317

Fiber-based femtosecond 3D printing — •Claudia Imiolczyk1, Andy Steinmann1, Moritz Flöß1, Zhen Wang1, Michael Heymann2, Andrea Toulouse3, and Harald Giessen114th Physics Institute, Research Center SCoPE, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany — 2Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany — 3Institute of Applied Optics, Research Center SCoPE, University of Stuttgart, Pfaffenwaldring 9, 70569 Stuttgart, Germany

Ultrashort laser pulses are often used in medical applications, for instance for soft-tissue surgeries. However, the progress on using such laser pulses for tissue structuring is rather marginal so far. Therefore, we aim to realize an endoscopic fiber-based femtosecond 3D printer to minimally invasively surgically repair organ damage on a micrometer scale. For this, high-power femtosecond laser pulses are required, in order to 3D print desired geometries with a microfluidic bio-ink using two-photon-lithography. We utilize ruled reflective diffraction gratings to pre-chirp laser pulses, as dispersion in optical fibers broadens these femtosecond laser pulses. We report on measurements of pulse duration, spectrum, compression, and nonlinear effects. These resulting 3D printed structures should be colonized with endogenous cells, analogous to the extracellular matrix. This could open a new area of endoscopic 3D printing of biomaterials inside the human body to revolutionize plastic micro-surgery, such as repairing defects in the heart of embryos or even repairs behind the eardrum at the auditory ossicles.

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