Dresden 2026 – scientific programme
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BP: Fachverband Biologische Physik
BP 14: Poster Session II
BP 14.47: Poster
Tuesday, March 10, 2026, 18:00–21:00, P2
Experimental Setup for the Irradiation of Organoids with High-Energy Electron Beams — •Laura Andrea Pastor Luque1, Natascha Thomas2, Victor Emde2, Carla Sprengel1, Antonio Tarzikhan2, Constantin Aniculaesei2, Thomas Heinemann2, Mirela Cerchez2, and Thomas Heinzel1 — 1Condensed Matter Physics Laboratory, Heinrich Heine University, Düsseldorf, Germany — 2Institut für Laser- und Plasmaphysik, Heinrich Heine University, Düsseldorf, Germany
Organoids are three-dimensional cell systems that mimic key physiological and structural characteristics of human tissues, making them highly relevant models for studying biological responses to ionizing radiation. However, experimental platforms for irradiating organoids with high-energy electron beams remain limited, particularly regarding precise dose control and sample handling. In this work, we present the design and development of an experimental irradiation setup specifically adapted for organoid cultures. The system integrates a high-energy electron beam source with a setup to irradiate organoids samples at different energy ranges (MeV).
Keywords: Electron Beam; Organoids; Ionizing Radiation; Medical Research