Dresden 2026 – scientific programme

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HL: Fachverband Halbleiterphysik

HL 2: Focus Session: Biocompatible Organic Semiconductors for Artificial Intelligence

HL 2.3: Invited Talk

Monday, March 9, 2026, 10:30–11:00, POT/0051

Organic Neuromorphic Interfaces for Biohybrid Systems: Material and Structural Biomimicry of Synaptic Plasticity — •Francesca Santoro — Forschngszentrum Jülich

Organic neuromorphic interfaces offer a promising route toward biohybrid systems that emulate neural function. We present PEDOT:PSS-based organic electrochemical transistors that exploit mixed ionic*electronic conduction and biocompatibility to reproduce key mechanisms of synaptic plasticity. Through the integration of bio-gels and azopolymer-functionalized conjugated polymers, neural activity is modulated by chemical and optical stimuli, enabling short- and long-term plasticity and interactions with neurotransmitters such as dopamine and glutamate. Beyond planar devices, 2.5D and 3D microfabricated organic semiconductor architectures fabricated by two-photon lithography or electrodeposition mimic neuronal morphology and promote cell adhesion and connectivity. The mechanical compliance of these materials supports stable interfacing with soft tissues, underscoring the role of material and structural biomimicry in next-generation organic biohybrid neuromorphic platforms.

Keywords: Organic neurohybrid interfaces