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ST: Fachverband Strahlen- und Medizinphysik
ST 5: Focus Session: Range Verification in Particle Therapy
ST 5.2: Invited Talk
Thursday, March 19, 2026, 11:30–12:00, KH 01.013
Carbon-ion radiotherapy monitoring with charged nuclear fragments — •Maria Martisikova1,2,3, Laurent Kelleter1,2,3, Rebekka Kirschgässner1,2,4, Pamela Ochoa1,2,4, Semi Harrabi5,6, Jan Jakubek7, Oliver Jäkel1,2,3,5, and Jürgen Debus2,3,5,6 — 1Heidelberg Institute for Radiation Oncology HIRO, National Centre for Research in Radiation Oncology NCRO — 2German Cancer Research Centre DKFZ, Department of Medical Physics in Radiation Oncology — 3National Center for Tumor Diseases (NCT) Heidelberg — 4Department of Physics and Astronomy, Heidelberg University — 5Department of Radiation Oncology, Heidelberg University Hospital — 6Heidelberg Ion-Beam Therapy Center (HIT) — 7ADVACAM s.r.o., U pergamenky 12, Prague, Czech Republic
Our group has been investigating the potential of measured secondary ion emission profiles to assess delivered dose distributions. A secondary-ion tracking system has been developed and successfully implemented in the clinical environment of the Heidelberg Ion Beam Therapy Facility. Within the InViMo clinical trial, secondary ion emission profiles have been measured during at least two treatment fractions for 35 patients to date. While the measured profiles were consistent between fractions for the majority of patients, pronounced inter-fractional changes were observed in several cases. These differences correlate with plausible anatomical locations.
Keywords: Carbon ion radiotherapy; monitoring; secondary ions; clinical ion tracker; clinical trial