Berlin 2001 – scientific programme
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Q: Quantenoptik
Q 38: Laser in Medicine
Q 38.3: Talk
Friday, April 6, 2001, 18:00–18:15, H 2013
Influence of the Erythrocyte Concentration on Laser Doppler Flow Measurement of Tissue Perfusion using Phantoms — •Jens Osterholz1, Hans Joachim Schwarzmaier2, and Peter Hering1 — 1Institute of Laser Medicine, Heinrich-Heine University Düsseldorf — 2Headquarters Applied Medical Technologies, Klinikum Krefeld
Laser doppler flowmetry (LDF) is a technique used for the optical determination of the dynamic properties of turbid media which is applied in medicine for the non invasive in vivo measurement of the perfusion of biological tissues. The tissue is illuminated with coherent laser light and the autocorrelation function of the intensity of the backscattered light is measured. Besides the speed of the erythrocytes, the autocorrelation function depends on the concentration of the erythrocytes in the illuminated volume. This effect has been examined using a tissue phantom on the basis of resin. The perfusion of the tissue is simulated by pumping solutions of intralipid in different dilutions through a tube in the phantom. The experimental data are compared with calculations based on the correlation transport equation. Medical applications are discussed.