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DY: Dynamik und Statistische Physik

DY 44: Synchronisation II

DY 44.1: Invited Talk

Thursday, March 27, 2003, 14:30–15:00, G\"OR/226

From stochastic phase resetting to stereotaxic therapy — •Peter Tass — Magnetoencephalography and Deep Brain Stimulation Lab, Institute of Medicine, Research Centre Jülich

Based on novel, effectively desynchronizing stimulation methods deep brain stimulation (DBS) techniques have been designed which aim at a desynchronization of pathologically synchronized neural activity. In contrast, the standard deep brain stimulation is a permanent high-frequency (> 100 Hz) electrical pulse train stimulation which basically suppresses the firing in particular target areas. However, synchronized activity in particular target areas is the hallmark of several neurological diseases like Parkinson’s disease, while under healthy conditions neurons in these areas fire in an uncorrelated way. The talk is about both theory and first experimental results.