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Dresden 2006 – wissenschaftliches Programm

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CPP: Chemische Physik und Polymerphysik

CPP 20: SYMPOSIUM Microfluidics I: Boundary conditions, manipulation, and transport

CPP 20.5: Hauptvortrag

Donnerstag, 30. März 2006, 11:00–11:30, ZEU 160

Sorting in Structured Microfluidic Devices — •Alexandra Ros1, Jan Regtmeier1, Thanh Tu Duong1, and Dario Anselmetti21Bielefeld University, Experimental Biophysics and Applied Nanoscience, Universitaetsstr. 25, 33615 Bielefeld, Germany — 2Biefeled University, Fakulät für Physik, D-33615 Bielefeld

Suitably tailored microfluidic devices open access to unexpected dynamics and migration phenomena for colloidal particles and molecules. Recently, absolute negative mobility, i.e. the motion opposite to a net acting force, was observed in a lab-on-a-chip for colloidal particles [1]. This non-equilibrium effect is based on Brownian motion and non-linear dynamics induced by microstructuring. Exploiting the sensitive dependence of this paradoxical effect on basic particle properties, we demonstrate the simultaneous migration of two different species of alike-charged particles into opposite directions. The application of this new migration phenomenon for the separation or sorting of biomolecules, cell compounds and cells will be discussed.

[1] A. Ros, R. Eichhorn, J. Regtmeier, T. Duong, P. Reimann, D. Anselmetti, Nature 436, 928 (2005)

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