Dresden 2006 – wissenschaftliches Programm

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CPP: Chemische Physik und Polymerphysik

CPP 27: POSTER Polymer Physics and Materials

CPP 27.27: Poster

Donnerstag, 30. März 2006, 17:00–19:00, P2

Formation of thermoresponsive hydrogel films via electrochemically initiated polymerization — •Johanna Reuber and Diethelm Johannsmann — Institute of Physical Chemistry, Arnold-Sommerfeld-Strasse 4, 38678 Clausthal-Zellerfeld

Electrochemically initiated polymerization has previously been employed to produce coatings on metals [1], where the interest mainly was in corrosion protection. We report on the extension of this technique to films of poly-(N-isopropylacrylamide) (p-NIPAM), which is a thermo-responsive hydrogel.[2] A free-radical polymerization is initiated via an electron transfer from the electrode to an electrochemically active initiator. The progress of polymerization was monitored by means of the electrochemical quartz crystal microbalance (EQCM). Typical thicknesses are in the range of up to 100 nm. The water content varies between 20 and 80 %. AFM micrographs reveal a globular structure. The permeation of ions through the gel is possible, as proven by CV runs in the presence of K3[Fe(CN)6] in the bulk. First experiments have been performed to explore biomedical applications such as cell-sheet engineering [3] or stimulated drug release [4]. In cell culture, the layers show low-fouling properties. A second application are polymer metal composites: galvanic deposition of copper particles onto the polymer-covered surface has been demonstrated. References: [1] N. Baute, C. Jérôme, et al., European Journal of Inorganic Chemistry 2001, 1097. [2] H.G. Schild, Progress in Polymer Science 1992, 17, 163. [3] A. Kikuchi, T. Okano, Journal of Controlled Release 2005, 101, 69. [4] A. Kikuchi, T. Okano, Advanced Drug Delivery Reviews 2002, 54, 53.