Regensburg 2007 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 26: Poster Session II
BP 26.44: Poster
Donnerstag, 29. März 2007, 17:00–19:30, Poster B
Lipid Assemblies on Nanostructures — •Jens Kühnle1,2, Joachim Spatz1,2, and Ralf Richter1,2 — 1Biophysikalische Chemie, University of Heidelberg, Germany — 2MPI for Metals Research, Stuttgart, Germany
The properties and biological functions of lipid membranes originate from a wealth of different lipid-lipid and lipid-protein interactions. In order to understand the relationship between molecular interactions and the behaviour of the membrane as a whole, simplified model systems have proven useful Here, we propose a new model system that is based on the combination of nanostructured surfaces and supported lipid membranes. Our nanostructuration approach allows for the deposition of arrays of nanometer-sized gold dots with tuneable inter-dot spacings on solid surfaces. We show that supported lipid membranes can be formed on such templates. We characterize the influence of local chemical and geometrical heterogeneities, as presented by the gold dots, on the mobility of lipid molecules by fluorescence recovery after photobleaching (FRAP). The features contained in these model systems might give new insights into the interaction mechanisms that underlie transport and phase separation in lipid membranes.