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BP: Fachverband Biologische Physik
BP 27: Nonequilibrium Processes and Self-Organisation
BP 27.8: Vortrag
Freitag, 30. März 2007, 12:30–12:45, H43
Cell morphology in growing tissues — •Reza Farhadi Far1, Jens-Christian Röper2, Suzanne Eaton2, and Frank Jülicher1 — 1Max-Planck-Institute for the Physics of Complex Systems, Nöthnitzer Straße 38, Dresden — 2Max-Planck-Institute for Molecular Cell Biology and Genetics, Pfotenhauer Straße 108, Dresden
We present a theoretical study of the morphology and topology of cell packing in a two dimensional tissue. Using a vertex model, we represent each cell by a polygon and take into account cell elastic properties, line tension due to adhesion with neighboring cells as well as contractility of the cell. We present a phase diagram of the model and study the topology and morphology of the cell packing in the presence of cell division. We find three distinct types of tissue morphology, depending on parameter values. We compare our calculations to observed cell packings in the wing-disc of the fruit fly Drosophila.