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MO: Fachverband Molekülphysik

MO 16: Biomoleküle

MO 16.9: Poster

Tuesday, March 11, 2008, 14:00–19:00, Poster C1

Radiation damage studies on water-embedded biomolecules — •Sadia Bari¹, Maarten Inklaar¹, Dominik Gosset², Femke van Seijen¹, Ronnie Hoekstra¹, and Thomas Schlathölter¹ — ¹KVI Atomic Physics, University of Groningen, The Netherlands — ²ENSIAME, Valenciennes, France

The current increasing social and corporate interest in proton- and heavy ion-therapy of malignant tumors now results in the construction of first particle treatment centers. The chemical and biological aspects of biological radiation damage have been studied in great detail. However, little is known about biological radiation action on the molecular level and fs-timescales. First studies focused on gas phase DNA related molecules and neglected influences of the chemical environment.

To investigate these influences we built an electrospray ionization (ESI) source to form clusters from DNA molecules surrounded by water. Cooling and mass selection in a RF quadrupole ion trap ensures sufficient cluster density. After keV-ion irradiation collision products are extracted from the trap into a time-of-flight mass spectrometer.