Dresden 2009 – wissenschaftliches Programm
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CPP: Fachverband Chemische Physik und Polymerphysik
CPP 13: POSTERS Polymer Physics
CPP 13.9: Poster
Dienstag, 24. März 2009, 14:00–16:30, P3
Dynamical properties of chain molecules in confinements and in variation of system properties: model of DNA segregation — •Ron Dockhorn1,2 and Jens-Uwe Sommer1,2 — 1Leibniz Institute of Polymer Research Dresden, D-01069 Dresden, Germany — 2Technische Universität Dresden, Institute for Theoretical Physics, D-01069 Dresden, Germany
Large chain molecules are studied and simulated in various conditions such as restricted geometries, interaction potential and solvent quality using the bond fluctuation method. How relaxation time, diffusion and segregation time are related due to strong confinements is analyzed and compared to scaling approaches. The investigations are also focused on the influence of topological constraints such as linear and circular polymers and excluded volume effect in confinements compared with theoretical predictions. The process of duplicating and segregating of chain molecules in cylindrical confinements is examined as a model of prokaryotic DNA during replication. Furthermore the model can be extended to study the influence of condensin, cohesin and topoisomerases in DNA condensation and segregation in eukaryotes.