DPG Phi
Verhandlungen
Verhandlungen
DPG

Regensburg 2010 – scientific programme

Parts | Days | Selection | Search | Downloads | Help

BP: Fachverband Biologische Physik

BP 31: Posters: Membranes and Vesicles

BP 31.3: Poster

Thursday, March 25, 2010, 17:15–20:00, Poster B1

Oscillations in the lateral pressure of lipid monolayers induced by the second messengers MARCKS and Protein Kinase C — •Sergio Alonso1, Markus Bär1, Undine Dietrich2, and Josef A. Käs21Physikalisch-Technische Bundesanstalt, Berlin, Germany — 2University of Leipzig, Leipzig, Germany

The binding dynamics of the peptide MARCKS to the lipid PIP2 modulated by protein kinase C leads to damped oscillations in lateral pressure of a lipid monolayer. These periodic dynamics can be attributed to changes in the crystalline lipid domain size. We elaborate a mathematical model to explain the observations based on the changes in the physical structure of the monolayer by the translocation of MARCKS peptides. The model equations are numerically integrated and reproduce the experimental observations.

100% | Mobile Layout | Deutsche Version | Contact/Imprint/Privacy
DPG-Physik > DPG-Verhandlungen > 2010 > Regensburg