Dresden 2011 – wissenschaftliches Programm
Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe
BP: Fachverband Biologische Physik
BP 20: Neurobiophysics
BP 20.4: Vortrag
Mittwoch, 16. März 2011, 11:15–11:30, ZEU 250
Spatio-temporal encoding of sound in the inferior colliculus — •Dominika Lyzwa1, Hubert H. Lim2, and J. Michael Herrmann3 — 1Dept. Nonlinear Dynamics, MPI for Dynamics and Self-Organization, Göttingen, Germany — 2Dept. Otolaryngology, Hanover Medical University, Germany — 3IPAB, School of Informatics, University of Edinburgh, U.K.
The inferior colliculus (IC) is an important stage in the auditory pathway. We study the spatio-temporal encoding taking place in the laminated central inferior colliculus. We analyze multi-unit activity (MUA) recorded from the IC in cats during acoustic stimulation with pure tones and in guinea pigs during stimulation with vocalizations of these animals as an example of natural stimulation.
Using linear discriminant analysis we obtain that for pure tone stimuli the classification into different stimulus categories is best for time intervals of the recording that contain the onset activity. The latency of the classification is found to be 5-10 ms, increasing from low to high stimulus tones. The information about the stimulus frequency is mostly contained in the first principal component of the response and at early latencies. In the recordings from the vocalization stimulation the dynamic correlations of the response properties from neuron populations along the tonotopic axis and in particular within an iso-frequency lamina are investigated. The results from pure tone and natural stimulation are combined to give a phenomenological model of spatio-temporal encoding in the ICC.