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BP: Fachverband Biologische Physik

BP 28: Statistical Physics in Biological Systems IV (joint DY, BP)

BP 28.3: Talk

Thursday, March 17, 2011, 14:30–14:45, ZEU 260

Statistical topography of fitness landscapes — •Jasper Franke¹, Alexander Klözer¹, J. Arjan G. M. de Visser², and Joachim Krug¹ — ¹Cologne University, Cologne, Germany — ²Wageningen University, Wageningen, Netherlands

The adaptive evolution of a population under the influence of mutations and selection is governed by the structure of the underlying fitness landscape. Previous theoretical studies of topographical quantities on fitness landscapes have mostly focused on local properties such as local maxima.

Here we investigate the global property of accessible paths traversing the complete genome configuration space towards the global optimum. Numerical and analytical studies and comparison to empirical data suggest a surprising unversality across almost all established theoretical models, indicating high accessibility of the globally optimal configuration in the biologically relevant limit of very long genome sequences.