Dresden 2011 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 35: Poster: Micro- and Nanofluidics

CPP 35.12: Poster

Mittwoch, 16. März 2011, 17:00–19:00, P2

Microparticle Separation in Droplet Based Microfluidics — •Michael Hein, Jean-Baptiste Fleury, and Ralf Seemann — Experimental Physics, Saarland University, Saarbrücken, Germany

To compartment extremely small liquid volumes into droplets and manipulate them in droplet based microfluidic systems offers the benefit of inhibiting dispersion and cross contamination of analytes. For many applications like cytometry, hemotology or immunoassays molecules are attached to microbeads and subsequently dispersed in various li-quids to achieve and probe certain reactions. To include those type of reactions into microfluidics devices we explore particle separation in droplets flowing in straight microfluidic channels.

Particle separation might occur inside a droplet and leads to a concentration of dispersed particles at either the front or the rear end of a droplet after a short travel distance. We explore the particle se-paration for several parameters like density difference of the particles and the dispersed phase, particle size, viscosities of the liquids, droplet size, channel geometry, and flow velocity. After concentrating the particles, the droplet can be split into fractions containing excess dispersed phase and a large concentration of particles, which then can be used for further microfluidic processing or analysis.