Dresden 2011 – wissenschaftliches Programm
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CPP: Fachverband Chemische Physik und Polymerphysik
CPP 39: Colloids and Complex Liquids II - Dynamics and Mechanical Properties
CPP 39.1: Vortrag
Donnerstag, 17. März 2011, 10:30–10:45, ZEU 222
Simplified particulate model for coarse-grained hemodynamics simulations — •Florian Janoschek1,2, Federico Toschi1,3, and Jens Harting1,2 — 1Eindhoven University of Technology, P.O. Box 513, 5600MB Eindhoven, The Netherlands — 2University of Stuttgart, Pfaffenwaldring 27, 70569 Stuttgart, Germany — 3CNR-IAC, Via dei Taurini 19, 00185 Rome, Italy
Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models either involve a homogeneous fluid and cannot track particulate effects or describe a relatively small number of cells with high resolution, but are incapable to reach relevant time and length scales. Our approach is to simplify much further than existing particulate models. We combine well established methods from other areas of physics in order to find the essential ingredients for a minimalist description that still recovers hemorheology. These ingredients are a lattice Boltzmann method describing rigid particle suspensions to account for hydrodynamic long range interactions and---in order to describe the more complex short-range behavior of cells---anisotropic model potentials known from molecular dynamics simulations. Paying detailedness, we achieve an efficient and scalable implementation which is crucial for our ultimate goal: establishing a link between the collective behavior of millions of cells and the macroscopic properties of blood in realistic flow situations. We present our model and demonstrate its applicability to conditions typical for the microvasculature.