Dresden 2011 – wissenschaftliches Programm
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Q: Fachverband Quantenoptik und Photonik
Q 36: Laseranwendungen und Photonik 1
Q 36.6: Vortrag
Mittwoch, 16. März 2011, 15:45–16:00, SCH 251
Updates on our non-invasive method to determine the total hemoglobin mass — •Marcus Sowa and Peter Hering — Institut für Lasermedizin, Universitätsklinikum Düsseldorf, Universitätsstr. 1, 40225 Düsseldorf
At the last DPG conference we presented first results of our work on a method to determine the total hemoglobin mass (t-Hb) in the human body. This non-invasive method is based on breath analysis by means of Cavity Leak-Out Spectroscopy (CALOS).
Our CALOS system works in the mid-infrared region at a wavelength of about 5 µm. This enables us to perform isotopologue selective online measurements of the P25 transition of 13CO at 1994.7 cm−1 without any cross sensitivities towards other relevant gases in the exhaled air. The advantage of the utilization of the rare isotopologue is the harmless amount of 13CO needed for the inhalation process.
We will report on various improvements regarding our system e.g. the sensitivity and the measurement of the t-Hb mass. The temperature stabilization of our CALOS cavity is subject of a separate talk at this conference as well as the subject of blood analysis regarding the isotopologue selective measurement of carboxyhemoglobin.
Furthermore, we have conducted our experiment before and after a blood donation. This allows us to check wheter our method is sensitive enough to detect sudden changes in the t-Hb mass as they would occur e.g. with blood doping. The results of these measurements are very promising and will also be presented in the talk.