Berlin 2012 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 18: Posters: Statistical Physics in Biological Systems
BP 18.38: Poster
Mittwoch, 28. März 2012, 17:30–19:30, Poster A
Modeling of rhythmic patterns in hippocampus — •Anastasia Lavrova1, Michael Zaks2, and Lutz Schimansky-Geier1 — 1Institut für Physik, HU — 2Institut für Mathematik
The hippocampal circuit can exhibit network oscillations in different frequency ranges (*gamma* - 30-80 Hz; *theta* - 4-12 Hz; as well as *theta/gamma* or a bursting regime) both in vivo and in vitro and switch between them. . The hippocampal neuronal network consists of various types of connected cells, which allows them to provide oscillations with different periods, amplitudes, and phase shifts.
We propose the minimalistic model for the description of generation of such polyrhythmic signals in the hippocampal area CA3. The network includes two fast- and two slowly-spiking cells which are described by the FitzHugh-Nagumo equations and coupled by means of synaptic connections. We analyze the influence of synaptic strengths on the synchronization in the network. Mechanisms of switching between different rhythms are discussed.