Berlin 2012 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 27: Posters: Cytoskeletal Filaments
BP 27.4: Poster
Donnerstag, 29. März 2012, 17:30–19:30, Poster A
Cortical dynamics with viscoelasticity — •Arnab Saha1, Stephan Grill1,2, Guillaume Salbreux1, and Frank Jülicher1 — 1Max Planck Institute (Physics for complex system) — 2Max Planck Institute (Molecular cell biology and Genetics)
The cell cortex is a thin layer beneath the cell membrane that largely consists of cross-linked actin filaments, non-muscle myosin motor-protein and various actin binding proteins (ABPs). It can actively contract and generate stress in presence of ATP-consuming motor proteins and treadmilling processes, that drive the cortex far away from thermal equilibrium. Here we present a two dimensional hydrodynamic model for cell cortex valid at long length scale and short to long time scales (incorporating both elastic and viscous regimes), using basic symmetry principles and conservation laws. Using the model, then we probe the elastic regime of cortical dynamics along with the experimental observations from laser ablation of cortex.