Berlin 2012 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 27: Poster: (Hydrogels) and Elastomers

CPP 27.6: Poster

Mittwoch, 28. März 2012, 11:00–13:00, Poster A

Structure-Function-Relationships in Biomimetic Hydrogels — •Valentin Hagel, Seraphine Wegner, Yvonne Schoen, Isabell Nuss, Tamas Haraszti, Heike Boehm, and Joachim Spatz — Max Planck Insitute for Intelligent Systems, Department New Materials and Biosystems, Stuttgart, Germany & University of Heidelberg, Department of Biophysical Chemistry, Heidelberg, Germany

Hydrogels are extensively studied as matrices for tissue engineering applications. The importance of these materials comes from their chemical versatility that allows for the design of a broad range of gels with tunable properties and their excellent biocompatibility due to their physical similarity to the native extracellular matrix. Engineering the mechanical and structural properties of hydrogels allows to design feasible materials for tissue repair implants. We present the analysis of hyaluronan-based hydrogels formed with a new type of biomimetic cross-linker. For the characterization of the polymer morphology and transport phenomena within the gels FRAP is used and a diffusion model is derived from the obtained data. Mechanical and rheological analyses are done on a mechanical testing system and a rotational rheometer. The results from both the mechanical and the diffusion analysis are correlated in order to establish structure-function-relationships.