Berlin 2012 – wissenschaftliches Programm
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HL: Fachverband Halbleiterphysik
HL 30: ZnO and Relatives I
HL 30.7: Vortrag
Dienstag, 27. März 2012, 11:00–11:15, EW 202
Biofunctionalization of ZnO Nanowires for DNA sensing applications — •Slowik Irma1, Barbara Seise2, Christian Leiterer2, Raphael Niepelt1, Ulrich Schröder2, Davide Cammi1, Wolfgang Fritzsche2, and Carsten Ronning1 — 1Friedrich-Schiller-Universität, Jena, Deutschland — 2Institut für Photonische Hochtechnologie, Jena, Deutschland
Reliable and efficient identification of DNA is a major goal in modern medical diagnostics. Here, we present a promising alternative approach to conventional fluorescence labeled DNA sensors. Bottom up fabricated ZnO nanowires were chemically modified to attach probe DNA on the surface of the nanowire. Successful binding and hybridization with the complementary DNA was shown using fluorescence labeled target DNA. Due to the quasi-one-dimensional geometry of the nanowires and the large surface-to-volume ratio, surface-induced effects can have a big impact on the electrical transport properties. Changes in surface composition that occur during absorption of molecules lead to significant changes in nanowire conductivity. The effect can be utilized to create an electrical device out of biofunctionalized nanowires for label-free specific sensing of biomolecules with high sensitivity. Electrical contacting of the nanowires can be conducted either by photolithography or dielectrophoresis.