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Regensburg 2013 – scientific programme

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BP: Fachverband Biologische Physik

BP 22: Biomechanics (joint focus session with jDPG)

BP 22.5: Talk

Wednesday, March 13, 2013, 16:30–16:45, H6

Dynamics of regenerating tissues under mechanical stress — •Claus Fütterer1,2, Julia Fischer1, Kao-Nung Lin1, and Michael Krahe11Fakultät für Physik und Geowissenschaften, Institut für Experimentelle Physik I, Universität Leipzig, 04103 Leipzig, Germany — 2ranslationszentrum für Regenerative Medizin (TRM), Universität Leipzig

Hydra vulgaris tissue fragments regenerate and provide an ideal system to study the relation of single cell mechanics to tissue mechanics. We studied tissue toroids with about 1500 cells and studied the overall force fluctuations as well as single cell behaviour. We also applied continuous stress as well as stress pulses to the tissue and investigated the active and passive relaxation and contraction dynamics. We relate the mechanical measurements to the alpha and beta actin structures which form well organized supra-cellular structures responsible for the orchestration of the regeneration process.

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