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Dresden 2014 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 25: Statistical Physics in Biological Systems (joint DY/BP)

BP 25.4: Vortrag

Mittwoch, 2. April 2014, 10:15–10:30, ZEU 160

Environmental effects on DNA denaturation — •Christian von Ferber1 and Yurij Holovatch21AMRC, Coventry University, Coventry, UK — 2Institute for Condensed Matter Physics, National Academy of Sciences of Ukraine, Lviv, Ukraine

We re-consider the Poland and Scheraga model for the DNA denaturation transition where the double DNA strands locally and then globally detach as the transition temperature is attained. Applying a polymer field theory approach we discuss in particular variants of this transition that may occur due to the properties of the environment. We show that different environments may shift the transition further or less towards a first order transition. Effects we discuss are: the presence of (1) uncorrelated and (2) power-law long-range correlated disorder where the latter influences the transition as function of the power law exponent,(3) quality of the solution which may affect the self- and mutual interaction of both single and double strands, and (4) combinations of these effects. We find that the effects studied significantly influence the transition.

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