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BP: Fachverband Biologische Physik

BP 43: Neurosciences

BP 43.1: Topical Talk

Friday, April 4, 2014, 09:30–10:00, ZEU 250

The Dynamics of Neuronal Circuits — •Fred Wolf — Max Planck Institute for Dynamics and Self-Organization — Bernstein Center for Computational Neuroscience, Göttingen University — Faculty of Physics, Göttingen University

Current advances in photonic live imaging, the ability to *instrument* living cells with genetically encoded sensors and effectors, and emerging techniques for the large-scale mapping of neuronal micro-circuits are currently driving a revolutionary change in the science of biological nervous systems. These advances are opening up exciting avenues for studying the collective dynamics and cooperative phenomena underlying the function of neuronal systems. This talk will first provide a condensed survey of emerging experimental techniques for observing and perturbing neuronal circuits. I will then present examples from our own theoretical and experimental work[1-8] on the dynamics of neocortical circuits that exemplify challenging dynamical systems and statistical physics problems that need to be solved to understand biological neuronal circuits.

[1]M. Kaschube et al., Science 330, 1113 (2010). [2]T. Tchumatchenko et al., Phys Rev Lett 104, 58102 (2010). [3]W. Wei and F. Wolf, Phys Rev Lett 106, 88102 (2011). [4]T. Tchumatchenko et al. J Neurosci 31, 12171 (2011). [5]M. Monteforte and F. Wolf, Phys Rev Lett 105, 1 (2010). [6]M. Monteforte and F. Wolf, Phys. Rev. X 2, 041007 (2012). [7]V. Ilin et al., Neurosci 33, 2281 (2013). [8]W. Keil et al., Science 336, 413 (2012).