Berlin 2015 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 16: Posters: Cell adhesion, mechanics and migration

BP 16.25: Poster

Montag, 16. März 2015, 17:30–19:30, Poster A

Viscoelastic mechanics of non-adhering cells — •Samaneh Rezvani Boroujeni, Abhinav Sharma, and Christoph F. Schmidt — 3rd Institute of Physics - Biophysics, Georg-August-Universität Göttingen, Germany

Cells sense their micro-environment through biochemical and mechanical interactions. They can respond to biochemical and mechanical stimuli by undergoing shape- and possibly volume-changes. To understand such responses, one needs a quantitative model for the mechanical properties of a cell. The key components in determining the mechanical response of a cell are the viscoelastic properties of the actomyosin cortex, effective surface tension, and the osmotic pressure. We probe suspended rounded-up cells by active and passive microrheology and construct a model to describe the roles of the various components.