Berlin 2015 – wissenschaftliches Programm
Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe
BP: Fachverband Biologische Physik
BP 22: Posters: Cytoskeletal filaments
BP 22.7: Poster
Dienstag, 17. März 2015, 14:00–16:00, Poster A
Elastic Properties and Morphological Instability of Semiflexible Filament Networks: Application to Dendritic Actin Networks — •Thomas Stöter1, 3, Karin John2, 3, Denis Caillerie4, 5, and Chaouqi Misbah2, 3 — 1Otto-von-Guericke Universität Magdeburg, FNW/ITP, D-39106 Magdeburg — 2Univ. Grenoble Alpes, LIPHY, F-38000 Grenoble, France — 3CNRS, LIPHY, F-38000 Grenoble, France — 4Univ. Grenoble Alpes, 3SR, F-38000 Grenoble, France — 5CNRS, 3SR, F-38000 Grenoble, France
Semiflexible filament networks form elastic materials that are ubiquitous in living cells, where they are transient, adapting to the current need of the cell to find food, escape predators etc. So, these networks grow and dissolve dynamically in response to external stimuli. We are interested in the complex interplay of network growth and mechanics that is, for example, used by the pathogen Listeria monocytogenes to propel itself forward inside a host cell.
We introduce a simple network model with a quasi-periodic topology and simple microscopic properties of the filaments. Despite its simplicity, this model reproduces several traits of the complex nonlinear behaviour of semiflexible filament networks observed in experiments. Combining the model with a growth law and solving the dynamics in a circular geometry on a two-dimensional disk, we find a growth instability that results from the mechano-chemical coupling of growth and mechanical stress. This instability may be interpreted as a symmetry breaking event commonly seen in biomimetic experiments of cell motility.