Hannover 2016 – wissenschaftliches Programm

Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe

Q: Fachverband Quantenoptik und Photonik

Q 32: Biophotonics

Q 32.8: Vortrag

Mittwoch, 2. März 2016, 12:45–13:00, f342

Simulation of the OCT-depth signal of homogeneous turbid media via an extended Monte-Carlo model — •Arthur Varkentin, Maya Otte, Merve Wollweber, Maik Rahlves, and Bernhard Roth — Hannoversches Zentrum für Optische Technologien - HOT, Leibniz Universität Hannover, Germany

Optical coherence tomography (OCT) is widely used for imaging of biological tissue. In most cases the result is a 2D or 3D tomogram showing scattering structures of the studied sample. This qualitative information indicates the morphology of the tissue. The extraction of quantitative information such as the scattering coefficient µ_s is straight forward only for weakly scattering media where ballistic photon scattering can be assumed. For highly scattering media, however, additional phenomena have to be taken into account. For example, multiple scattering has to be considered, where photons that are scattered more than once, but are still within the coherence length of the OCT also contribute to the signal. A cluster of equal scatterers can appear as one single scatterer with different optical properties. These effects lead to concentration dependent scattering which shows non-linear behavior. We present a simple model to simulate OCT-depth signals in weakly and strongly scattering media. Multiple scattering is implemented and, in addition, a weighting function rescales the photon signal according to the number of undergone scattering events. Based on a parameter study of this weighting function we are able to implicitly predict the influence of dependent scattering without modeling the process explicitly. In future, our quantitative approach could improve biological imaging.