Hannover 2016 – wissenschaftliches Programm

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SYBO: Symposium Biomedical Optics

SYBO 1: Symposium Biomedical Optics 1

SYBO 1.1: Hauptvortrag

Donnerstag, 3. März 2016, 11:00–11:30, e415

Recent advances of Optical Coherence Tomography — •Wolfgang Drexler — Zentrum für Medizinische Physik und Biomedizinische Technik, Medizinische Universität Wien

Optical coherence tomography (OCT) is one of the most rapidly emerging and innovative optical imaging modalities of the last decades enabling in vivo cross-sectional tomographic visualization of internal microstructure in biological systems. Recent developments in ultrabroad bandwidth laser as well as OCT technology enable three-dimensional ultrahigh resolution OCT with unprecedented axial resolution, approaching resolution levels of con-ventional histopathology, enabling optical biopsy of biological tissue. In addition, multimodal extensions of OCT are recently under development that should provide non-invasive depth resolved functional imaging of the investigated tissue, including extraction of spectroscopic, blood flow or physiologic tissue information. These extensions of OCT should not only enable sub-cellular resolution imaging, improve image contrast, but should also enable the differentiation and early detection of pathologies via localized biochemical, molecular properties or functional state. The hypothesis is to provide (sub)cellular level resolution visualization of tissue morphology (optical biopsy) and at the same time localized metabolic, molecular and physiologic tissue information in performing a single volumetric multimodal OCT measurement.