Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 53: Posters - Statistical Physics of Biological Systems

BP 53.8: Poster

Mittwoch, 9. März 2016, 17:00–19:00, Poster C

Stuttering of Min oscillations is induced by stochastic effects — •Lukas Wettmann and Karsten Kruse — Theoretische Physik, Universität des Saarlandes, Postfach 151150, 66041 Saarbrücken, Germany

The site of cell division in wild type E. coli bacteria is determined through pole-to-pole oscillations of the Min proteins. Although the oscillations are fairly stable across a wide variety of cell shapes and protein concentrations the emerging patterns are subject to molecular noise, due to the small copy number of proteins in a single cell. This causes the oscillations to sometimes "stutter" and remain in the same polar configuration. We used a model based on transient binding of MinE to the cytoplasmic membrane to describe the dynamics of the Min system and analyzed the stochastic dynamics in the limit of weak noise.