Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 66: Biomaterials and Biopolymers III (Joint Session BP/CPP/MM)

BP 66.3: Vortrag

Donnerstag, 10. März 2016, 15:30–15:45, H45

Different protein adsorption rates on different grain orientations in hydroxyapatite — •Thomas Faidt, Jörg Schmauch, Michael Deckarm, Samuel Grandthyll, Frank Müller, and Karin Jacobs — Saarland University, Dept. of Experimental Physics, 66041 Saarbruecken

As a model system for tooth enamel, hydroxyapatite (HAP) pellets with a density of > 97% of the theoretical crystallographic density of HAP have been produced by compacting and sintering commercially available HAP powder. Atomic force microscopy (AFM) combined with electron backscatter diffraction (EBSD) measurements reveal the smoothness and the crystal orientation of the HAP grains on the surface of the pellets. On these surfaces, single molecule BSA adsorption experiments are performed in a microfluidic setup and reveal that different grain orientations provoke different adsorption rates. These findings open a pathway to control protein adsorption.