Dresden 2017 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 23: Posters - Statistical Physics of Biological Systems

BP 23.8: Poster

Dienstag, 21. März 2017, 14:00–16:00, P1A

Predictability of mutational trajectories in evolutionary rescue — •Jan Schmidt and Joachim Krug — THP, Cologne

Predictability of evolutionary pathways has been considered in terms of the strong selection weak mutation model (SSWM), where the whole population moves monomorphically along pathways with increasing fitness while maintaining a constant population size [1,2]. We compare these trajectories to pathways that are taken by a population which is on the verge of extinction. Here, conceptually, the assumption of SSWM is no longer valid. Dropping the constraint of fixed population size, where the population does not fixate the intermediate types before the rescuing type is reached, this process is described in terms of a branching process [3].

[1] D.M. Weinreich et. al., Science 312, 111 (2006)

[2] J. Franke et. al., PLoS Comput Biol 7, e1002134 (2011)

[3] B. Bauer and C. Gokhale, Scientific Reports 5, 9607 (2015)