Dresden 2017 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 26: Posters - Cell Adhesion
BP 26.3: Poster
Dienstag, 21. März 2017, 14:00–16:00, P2-EG
Microbial Adhesion Influenced by Nanoroughnesses — Claudia Lüdecke-Beyer1,3, Martin Roth2,3, Nathalie Stefani2,3, •Christian Helbing1, Jörg Bossert1,3, and Klaus D. Jandt1,3 — 1Chair of Materials Science, Otto Schott Institute of Materials Research, Friedrich Schiller University, Jena, Germany — 2Leibniz Institute for Natural Product Research and Infection Biology, Bio Pilot Plant, Hans Knöll Institute, Jena, Germany — 3Jena School for Microbial Communication (JSMC), Excellence Graduate School, Friedrich Schiller University, Jena, Germany
An advanced understanding of the microbe-material-interaction is required for the current development and progress in nanoscale structuring of materials surfaces to control microbial adhesion. This study aimed to investigate the nanostructure of the microbe-material-interface and to link it to microbial adhesion kinetics as a function of the titanium surface nanoroughness. A statistically significantly reduced microbial adhesion on titanium surfaces, prepared by physical vapor deposition, with a nanoroughness of 6 nm compared to 2 nm was observed. Direct insight into the microbe-titanium-interface was gained by cross-sectioning of the microbial cells with a focused ion beam. High resolution scanning electron microscopy images gave first evidence that the surface peaks are the loci of initial contact between the microbial cells and the materials surface which is proposed in a qualitative model. This new understanding will help towards the design of materials surfaces for controlling microbial adhesion.