Dresden 2017 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 31: Posters - Biotechnology and Bioengineering

BP 31.1: Poster

Dienstag, 21. März 2017, 14:00–16:00, P2-OG1

Synthesis and charcterization of magnetite nanoparticles with aminosilane coating — •Stefanie Fuchs, Maryam Youhannayee, and Mathias Getzlaff — Institute of Applied Physics, Heinrich-Heine-Universität, Düsseldorf, Germany

The interest in magnetic nanoparticles grew in the recent years due to a wide range of possible applications in technology and medicine. The most important ones in medical and biomedical science are their use as MRI contrast agent, in targeted drug delivery and in hyperthermia treatment. They show superparamagnetic property at room temperature from the aspect of magnetic properties and also biocompatibility and low toxicity from a biomedical point of view. Magnetite nanoparticles are synthesized from Ferric Chloride and Ferrous Sulphate via wet chemical coprecipitation method. In order to functionalize them we have tried three different methods to coat them with N-(2-aminoethyl)-3-aminopropyltrimetoxysilane (AEAPS). The aminosilane ligand shell increases the stability of magnetite nanoparticles in solution and also biocompatibility of iron seeds thorough injection. The obtained particles have been characterized with Fourier transformed infrared spectroscopy (FTIR), X-ray powder diffraction (XRD) and transmission electron microscopy(TEM) to study the morphological structure of particles.