Dresden 2017 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 35: Posters - Physics of Parasites (Focus Session)

BP 35.2: Poster

Dienstag, 21. März 2017, 14:00–16:00, P2-OG1

The physical principles of a novel malaria diagnostic device — •Tamas Prok1, Adam Butykai1, Agnes Orban1, Petra Molnar1, Maria Pukancsik1, Tivadar Zelles2, Stephan Karl3, and Istvan Kezsmarki11Department of Physics, Budapest University of Technology and Economics and MTA-BME Lendület Magneto-optical Spectroscopy Research Group, 1111 Budapest, HU — 2Department of Oral Biology, Semmelweis University, 1089 Budapest, HU — 3Infection and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, AU

A novel cost-effective, automated, yet sensitive diagnostic method is needed for malaria detection both as an in-field instrument and as a laboratory tool for malaria researchers. Our group has developed the prototype of such device based on the detection of the magnetically induced linear dichroism of the malaria pigment crystals (hemozoin). These micrometer-size crystals are promising malaria-diagnostic targets as they are unique indicators of the infection exhibiting specific magnetic and optical properties. I am going to present our investigations unravelling the details of their anisotropic magnetic properties and linear dichroism; and I am going to show how these findings led us to the development of a highly sensitive detection setup comprising of a cheap laser diode, permanent magnets, simple polarization optics and computer-based data collection and analysis.

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