Dresden 2017 – wissenschaftliches Programm
CPP 14.3: Poster
Montag, 20. März 2017, 18:30–21:00, P1C
Study of the ion channels insertion in artificial membranes — Marcelo Cisternas1,2, Vanessa Zepeda1,2, Maria Jose Retamal1,2,5, Tomas P. Corrales3, Nicolas Moraga1,2, Diego Diaz1,2, Rodrigo Catalan1,2, Sebastian Gutierrez4, Tomas Perez-Acle4, Patrick Huber6, and •Ulrich G. Volkmann1,2 — 1Instituto de Fisica, P. Univ. Catolica de Chile (UC), Santiago, Chile — 2CIEN-UC, P. Univ. Católica de Chile (UC), Santiago, Chile — 3Facultad de Fisica, UTFSM, Valparaiso, Chile — 4DLab, Fundacion Ciencia y Vida, Santiago, Chile — 5Facultad de Quimica, P. Univ. Catolica de Chile (UC), Santiago, Chile — 6Institute of Materials Physics and Technology, TUHH, Hamburg, Germany
The study of artificial membranes is important, because these model-membranes represent the behavior of its biological analogs, with a similar structure, composed of a series of phospholipids and proteins, altering their behavior when exposed to physical and chemical stimulations. This motivates possible applications, for example in the detection and transduction of molecular signals, a very important step in the development of biosensors. In this research we measured the change in the capacitive response of a system, composed by a DPPC bilayer on a thin layer of Chitosan (CH) deposited on a silicon substrate. The system was immersed into a protein solution of gramicidin and the study of the change of the capacitive response confirms the ion channel formation in the bilayer. Acknowledgements: MJR: Fondecyt postdoc 3160803. UGV: Fondecyt 1141105 y CONICYT-PIA ACT 1409. TPC: Fondecyt Iniciación 11160664, MC: CONICYT scolarship.