Dresden 2017 – wissenschaftliches Programm
CPP 2.1: Hauptvortrag
Montag, 20. März 2017, 09:30–10:00, SCH A251
Cilia-based transport networks — •Eberhard Bodenschatz — MPI für Dynamik und Selbstorganisation , Am Fassberg 17, 37077 Goettingen
Cerebrospinal fluid conveys many physiologically important signaling factors through the ventricular cavities of the brain. We investigated the transport of cerebrospinal fluid in the third ventricle of the mouse brain and discovered a highly organized pattern of cilia modules, which collectively give rise to a network of fluid flows that allows for precise transport within this ventricle. Our work suggests that ciliated epithelia can generate and maintain complex, spatiotemporally regulated flow networks. I shall also show results on how to assemble artificial cilia and cilia carpets. This work is in collaboration with Regina Faubel, Gregor Eichele, Christian Westendorf, Azam Gholami, Isabella Guido, Yong Wang, Albert Bae and Marco Tarantola. Support by the Max Planck Society and the BMBF within the MaxSynBio initiative is gratefully acknowledged.